2013 Publications

The microglial sensome revealed by direct RNA sequencing.
Hickman SE, Kingery ND, Ohsumi TK, Borowsky ML, Wang L, Means TK, El Khoury J.
Nature Neuroscience

Successful noninvasive trisomy 18 detection using single molecule sequencing.
Van den Oever JM, Balkassmi S, Johansson LF, Adama van Scheltema PN, Suijkerbuijk RF, Hoffer MJ, Sinke RJ, Bakker E, Sikkema-Raddatz B, Boon EM.
Clinical Chemistry

RNA editing regulates transposon-mediated heterochromatic gene silencing.
Savva YA, Jepson JE, Chang YJ, Whitaker R, Jones BC, St Laurent G, Tackett MR, Kapranov P, Jiang N, Du G, Helfand SL, Reenan RA.
Nature Communications

On the importance of small changes in RNA expression.
St Laurent G, Shtokalo D, Tackett MR, Yang Z, Vyatkin Y, Milos PM, Seilheimer B, McCaffrey TA, Kapranov P.
Methods

Assessing the validity and reproducibility of genome-scale predictions.
Sugden LA, Tackett MR, Savva YA, Thompson WA, Lawrence CE.
Bioinformatics

Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila
St Laurent G, Tackett MR, Nechkin S, Shtokalo D, Antonets D, Savva YA , Maloney R, Kapranov P, Lawrence CE, Reenan RA
Nature Structural & Molecular Biology

VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer.
​ St Laurent G, Shtokalo D, Dong B, Tackett MR, Fan X, Lazorthes S, Nicolas E, Sang N, Triche TJ, McCaffrey TA, Xiao W, Kapranov P.
​ Genome Biology
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​Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lung.
​ Wong SM, Bernui M, Shen H, Akerley BJ.
Proceedings of the National Academy of Science U S A

​Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
Kerenyi MA, Shao Z, Hsu Y, Guo G, Luc S, O’Brien K, Fujiwara Y, Peng C, Nguyen M, Orkin SJ
eLife

​Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse
​Orlando L, GinolhacA , Zhang G, Froese D, Albrechtsen A, Stiller M, Schubert M, Cappellini E, Petersen B, Moltke I, Johnson P, Fumagalli M, Vilstrup JT, Raghavan M, Korneliussen T, Malaspinas AS, Vogt J, Szklarczyk D, Kelstrup CD, Vinther J, Dolocan A, Stenderup J, Velazquez AM, Cahill J, Rasmussen M et al.
Nature

Transcription Termination and Chimeric RNA Formation Controlled by Arabidopsis thaliana FPA
Duc C, Sherstnev A, Cole C, Barton GJ, Simpson GG
PLOS Genetics